Structural biology is being revolutionized at ASU using femtosecond nanocrystallography. Our faculty and students are defining the roles of enzymes and protein complexes with biomolecules that regulate transcription, translation, post-translational modification and energy and proton flow in DNA, in membranes and within cells. We also study the molecular basis of biology in geology and even astronomy.
Faculty
Protein structure and function, X-Ray crystallography, photosynthesis, bacterial cofactors
Structure, function and evolution of ribonucleoprotein complexes, RNA-protein interactions, telomerase biogenesis and mechanism
Electron microscopy, cryo-EM, electron crystallography, membrane protein, structural biology, signal processing, image processing
Microbiomes, Microscale Microbial Ecology, Carbon Sequestration, Host-Microbiome Interactions
Microfluidics, bioassays, microchip devices, Noninvasive sampling, materials and surface chemistry
Molecular modeling, biomolecular interactions and solvation, intermolecular vibrations, molecular crowding, complex formation and self-assembly
Bioinorganic chemistry, electrochemistry, hydrogenases, de novo protein design and engineering, redox enzyme mechanisms, alternative energy generation
Biomolecular structure, dynamics, interactions and functions. Translational research
Structure and function of nucleoprotein complexes; bacterial immune systems; CRISPR-Cas; RNA modifications; engineering genome editing tools
Biophysical chemistry, photophysics, single-molecule fluorescence, DNA-protein dynamics
Scanning probe microscopy, molecular electronics, molecular biophysics, nano-scale self-assembly
Protein Engineering, Computational Protein Design, Unnatural Amino Acids, Directed Evolution
Photosynthesis, protonmotive force, proton and electron transfer, photochemistry, photobiology, bioenergy, biocatalysis, sustainable energy, dye sensitized semiconductors
Theoretical chemistry, nanoscience, electron transfer, molecular conductance, nanomagnetism, chirality
Bacterial dynamics Single molecule Spectroscopy and Imaging analysis Stochastic processes Bayesian inference
marine biology, biochemistry, biomineralization, geochemistry, symbiosis, reef-building coral, mollusk, cnidarian
Molecular dynamics simulations, Cryo-electron microscopy, X-ray crystallography, hybrid modeling
Protein- and peptide-DNA nanotechnology, organic bioconjugation chemistry, self-assembly, nano-machines and devices, materials for biology and medicine
Coarse-grained modeling of DNA and RNA with applications to DNA/RNA nanotechnology, RNA folding, Molecular simulations to study properties of DNA and RNA in vivo and in vitro, Applications of statistical physics modeling to complex systems
Biochemistry, NMR, protein, carbohydrate, glycan, glycosaminoglycan, protein structure, protein-carbohydrate interactions
Experimental quantum biosensing; biophysics and protein sciences; diamond material; NMR; microscopy
Microbe-Nanostructure Interactions, Biogenic Nanomaterials, Amorphous Nanomaterials, Materials Crystal Structure and Catalysis, Anoxygenic Photosynthesis, Sulfur Bacteria, Sulfate-Reducing Bacteria, Biogeochemistry, and Astrobiology