Medicinal Chemistry

ASU students are at the forefront in describing the molecular basis of disease and critical protein/drug interactions with atomic-scale resolution. We are developing sensors for the early detection of disease, using biophysics and novel analytics for disease diagnosis at the atom, molecule and cell level, designing new drugs that target specific metabolic pathways, and are building high-throughput diagnostic arrays for personalized medicine.

James Allen

Protein structure and function, X-Ray crystallography, photosynthesis, bacterial cofactors

Kyle Biegasiewicz

Sustainable Synthesis, bioinspired Catalyst Development, biocatalysis, total synthesis

Chad Borges

Analytical biochemistry, mass spectrometry, protein posttranslational modifications, disease markers

 Petra Fromme

Structural biochemistry and biophysics, membrane proteins, X-Ray crystallography, photosynthesis, molecular biology

 Giovanna Ghirlanda

De-novo protein design and engineering, enzyme mechanisms, protein structure

Jia Guo

Novel fluorescent probes, single cell genomics and proteomics, cancer biology, neuroscience

Mark Hayes

Microfluidics, bioassays, microchip devices, Noninvasive sampling, materials and surface chemistry

Sidney Hecht

Improved diagnoses and treatments for diseases caused by impaired energy metabolism

Joshua LaBaer

Proteomics, biomarkers, cancer, diagnostics, protein arrays

Wei Liu

Biophysics, Drug Design, X-Ray Crystallography, G Protein–Coupled Receptors (GPCRs), Membrane Proteins, Lipidic Cubic Phase (LCP), Protein-Protein Interactions/Complexes, Protein Functions

Alexandra Ros

Micro and nanofluidics Bioanalytics, Single cell analysis, Biomolecule migration mechanisms

Wade Van Horn

Membrane proteins, Solution NMR, Structural biology, Biophysical Chemistry, Enzymology, Electrophysiology, Computational structural biology, Ion channels, Membrane enzymes

Peter Williams

Mass spectrometry, MALDI, DNA, sequencing, DNA Arrays