Medicinal Chemistry

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ASU students are at the forefront in describing the molecular basis of disease and critical protein/drug interactions with atomic-scale resolution. We are developing sensors for the early detection of disease, using biophysics and novel analytics for disease diagnosis at the atom, molecule and cell level, designing new drugs that target specific metabolic pathways, and are building high-throughput diagnostic arrays for personalized medicine.

Faculty

James Allen
Professor

Protein structure and function, X-Ray crystallography, photosynthesis, bacterial cofactors

Chad Borges
Associate Professor

Analytical biochemistry, mass spectrometry, protein posttranslational modifications, disease markers

Petra Fromme
Regents Professor, Paul V. Galvin Professor

Structural biochemistry and biophysics, membrane proteins, X-Ray crystallography, photosynthesis, molecular biology

Giovanna Ghirlanda
Professor

De-novo protein design and engineering, enzyme mechanisms, protein structure

Jia Guo
Associate Professor

Novel fluorescent probes, single cell genomics and proteomics, cancer biology, neuroscience

Mark Hayes
Professor

Microfluidics, bioassays, microchip devices, Noninvasive sampling, materials and surface chemistry

Sidney Hecht
Professor

Improved diagnoses and treatments for diseases caused by impaired energy metabolism

Joshua LaBaer
Professor, and Executive Director, Biodesign Institute

Proteomics, biomarkers, cancer, diagnostics, protein arrays

Wei Liu
Assistant Professor

Biophysics, Drug Design, X-Ray Crystallography, G Protein–Coupled Receptors (GPCRs), Membrane Proteins, Lipidic Cubic Phase (LCP), Protein-Protein Interactions/Complexes, Protein Functions

George Pettit
Regents Professor

Medicinal Chemistry, chemistry of natural products, discovery of new anti-cancer and anti-infective drugs for human cancer treatment

Alexandra Ros
Professor

Micro and nanofluidics Bioanalytics, Single cell analysis, Biomolecule migration mechanisms

Wade Van Horn
Associate Professor

Membrane proteins, Solution NMR, Structural biology, Biophysical Chemistry, Enzymology, Electrophysiology, Computational structural biology, Ion channels, Membrane enzymes

Peter Williams
Professor

Mass spectrometry, MALDI, DNA, sequencing, DNA Arrays