Medicinal Chemistry
ASU students are at the forefront in describing the molecular basis of disease and critical protein/drug interactions with atomic-scale resolution. We are developing sensors for the early detection of disease, using biophysics and novel analytics for disease diagnosis at the atom, molecule and cell level, designing new drugs that target specific metabolic pathways, and are building high-throughput diagnostic arrays for personalized medicine.
Protein structure and function, X-Ray crystallography, photosynthesis, bacterial cofactors
Analytical biochemistry, mass spectrometry, protein posttranslational modifications, disease markers
Structural biochemistry and biophysics, membrane proteins, X-Ray crystallography, photosynthesis, molecular biology
De-novo protein design and engineering, enzyme mechanisms, protein structure
Novel fluorescent probes, single cell genomics and proteomics, cancer biology, neuroscience
Microfluidics, bioassays, microchip devices, Noninvasive sampling, materials and surface chemistry
Improved diagnoses and treatments for diseases caused by impaired energy metabolism
Proteomics, biomarkers, cancer, diagnostics, protein arrays
Aedes aegypti mosquito; Proteases; Protein Structure and Function; Viral Pathogens
Micro and nanofluidics Bioanalytics, Single cell analysis, Biomolecule migration mechanisms
Membrane proteins, Solution NMR, Structural biology, Biophysical Chemistry, Enzymology, Electrophysiology, Computational structural biology, Ion channels, Membrane enzymes
Mass spectrometry, MALDI, DNA, sequencing, DNA Arrays