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A team of scientists from Arizona State University’s School of Molecular Sciences has begun rethinking the evolutionary history of photochemical reaction centers (RCs). Their analysis was recently published online in Photosynthesis Research and describes a new pathway that ancient organisms may have taken to evolve the great variety of photosynthetic RCs seen today across bacteria, algae, and plants. The study will go into print later this summer in a special issue dedicated to photochemical RCs.
This spring, the SMS online degree program team welcomed a new member, chemical education specialist Ara Austin. In her first semester with SMS as clinical assistant professor and coordinator of online programs, Ara is focused on ensuring the success of SMS’ first cohort of fully online biochemistry students.
On Monday, April 16, Arizona State University's School of Molecular Sciences held its annual award and recognition ceremony for outstanding students, research and teaching assistants, faculty members and their families. The ceremony recognized undergraduate and graduate students who excelled in academics and research, distinguished instructors and faculty, and spring 2018 doctoral and master's degree graduates.
April 11, 2018
Two ASU juniors win prestigious Goldwater Scholarship
SMS juniors Humza Zubair and Meilin Zhu have won Goldwater Scholarships, the most prestigious national award for undergraduates in math, science and engineering. Zhu, a biochemistry major, and Zubair, a biochemistry and biological sciences double-major, are both students in the School of Molecular Sciences and Barrett, The Honors College.
Arizona State University's School of Molecular Sciences has set out on a mission to change the societal underrepresentation of women in science, starting with its own project, Spotlight on Women in Science. Launching a social media campaign including sharing alumnae stories on Facebook and creating a collage video, this project highlights the power and importance of women in science.
A team led by Arizona State University scientists has found an explanation for the long-standing question of why the material that made the planets has a composition different from the sun's. James Lyons, associate research professor of astrophysics and cosmochemistry in ASU's School of Earth and Space Exploration and lead author on the paper, and co-authors Ehsan Gharib-Nezhad of ASU's School of Molecular Sciences and Thomas Ayres of the University of Colorado have published their findings recently in the journal Nature Communications.
On Tuesday, May 8, the College of Liberal Arts and Sciences at Arizona State University will recognize its highest achieving students from the social sciences, natural sciences and humanities at the 2018 convocation ceremony. Each department and school within the college has selected a phenomenal student who has demonstrated a steadfast commitment to academic excellence during their time at ASU.
March 9, 2018
Investigating the shapes of water
Arizona State University chemist C. Austen Angell, a Regents' Professor in ASU’s School of Molecular Sciences, has spent a good portion of his distinguished career tracking down some of water’s more curious physical properties. In a new piece of research published in Science on March 8, Angell and colleagues from the University of Amsterdam have, for the first time, observed one of the more intriguing properties predicted by water theoreticians — that, on sufficient super-cooling and under specific conditions, it will suddenly change from one liquid to a different one.
Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA “repeats” (specific DNA segments of six nucleotides) onto chromosome ends, and so afford immortality in cells. Understanding the underlying mechanism of telomerase action offers new avenues toward effective anti-aging therapeutics.
February 15, 2018
ASU alumnus wants to bridge gap between graduates and employers
Micah Wimmer, a triple Arizona State University alumnus and chemistry instructor at ASU's School of Molecular Sciences, hopes to use his diverse exposure to life on campus by uniting existing communities and inspiring progress across the College of Liberal Arts and Sciences and the university at large.
Professor Gary Moore, an assistant professor in Arizona State University's School of Molecular Sciences, has recently been recognized by ARCS for his work as a doctoral adviser. Moore has a passion for chemistry that is evident from the very first classes students take with him. He lectures on technical concepts in a logical and effective manner, and also addresses scientific topics in a context which brings students a level of cultural relevance to the subject matter that is rarely found in chemistry classes.
February 12, 2018
Cancer-fighting nanorobots seek and destroy tumors
In a major advancement in nanomedicine, Arizona State University scientists, in collaboration with researchers from the National Center for Nanoscience and Technology (NCNST) of the Chinese Academy of Sciences, have successfully programmed nanorobots to shrink tumors by cutting off their blood supply. The successful demonstration of the technology, the first-of-its-kind study in mammals utilizing breast-cancer, melanoma, ovarian and lung-cancer mouse models, was published in the journal Nature Biotechnology.
February 8, 2018
Old drug may have new tricks for fighting cancer
In a new study, researchers at Arizona State University’s Biodesign Institute used an innovative method to screen a broad range of kinases for a drug’s effectiveness. The compound, known as ibrutinib — an inhibitor of Bruton’s tyrosoine kinase (BTK) in white blood cells, was first approved by the FDA in 2013 for the treatment of leukemia. Using a sophisticated microarray platform invented by Joshua LaBaer, the new research demonstrates that ibrutinib can also target a little-studied member of the RTK family, known as ERBB4, potentially thwarting the sequence of events leading to progression and growth of other solid tumors.
December 14, 2017
'DNA origami' is the shape of things to come for nanotechnology
A team of Arizona State University and Harvard scientists including Hao Yan, director of the ASU Biodesign Institute’s Center for Molecular Design and Biomimetics, and the Milton Glick Professor in the School of Molecular Sciences professor, has invented a major new advance in DNA nanotechnology. Dubbed “single-stranded origami” (ssOrigami), their new strategy uses one long noodle-like strand of DNA, or its chemical cousin RNA, that can self-fold — without even a single knot — into the largest, most complex structures to date.
The College of Liberal Arts and Sciences at Arizona State University recognized its highest achieving students from the social sciences, natural sciences and humanities at the 2017 convocation ceremony. Jonathan Vie received the CLAS Dean's Medal for the School of Molecular Sciences.
November 15, 2017
Learning from photosynthesis
Hao Yan and Neal Woodbury from Arizona State University's Biodesign Institute and colleagues from Harvard and MIT are exploring new methods to capitalize on nature’s light-harvesting secrets. Their new study outlines the design of a synthetic system for energy gathering, conversion and transport that may point the way to innovations in solar energy, materials science, nanotechnology and photonics.
Changing the way the nation generates and consumes energy is at the heart of a new NSF grant awarded to Arizona State University and Kevin Redding, professor in the School of Molecular Sciences and director of the Center for Bioenergy and Photosynthesis (CB&P). The goal of Redding and his research group is to obtain industrial scale algal hydrogen production, which will require an improvement over current technology by at least five-fold.
ASU biophysicist Stuart Lindsay's research team has found evidence of a protein that can conduct electricity like a metal. Lindsay and his research group have published their new findings in the advanced online edition of the Institute of Physics journal Nano Futures.
The Chronicle of Higher Education has named Ariel Anbar, a President’s Professor in Arizona State University’s School of Earth and Space Exploration and School of Molecular Sciences, to its first-ever list of “Teaching Innovators.” The Chronicle calls these innovators “faculty members who are using fresh approaches in their classrooms to help their students succeed.”
A team of ASU scientists led by Professor Alexandra Ros in the School of Molecular Sciences and the Biodesign Center for Applied Structural Discovery, has been just the second user group to conduct experiments at the brand new European X-ray free electron laser facility (EuXFEL) in Hamburg, Germany. This 1.5-billion-dollar facility is the third, and far the most powerful, X-ray laser in the world.
October 10, 2017
ASU professor wins $2.1M NIH New Innovator Award
The National Institutes of Health (NIH) has awarded a five-year, $2.1 million grant to Alexander Green, Arizona State University Biodesign Institute professor and School of Molecular Sciences faculty member, to pursue innovative approaches to major contemporary challenges in biomedical research.
F. G. Keyes Professor of Chemistry at M.I.T. Richard R. Schrock, a Nobel laureate with many internationally contested awards, will be the featured Eyring Lecture Series speaker, Oct. 19 and 20, on Arizona State University's Tempe campus.
August 25, 2017
ASU team shines new light on photosynthesis
A team of scientists including School of Molecular Sciences Professors Kevin Redding and Raimund Fromme, as well as SMS doctoral student Chris Gisriel, has recently published an article in Science describing the structure of a reaction center from a heliobacterium that preserves the characteristics of the ancestral one, providing new insight into the evolution of photosynthesis.
August 18, 2017
ASU molecular sciences students excel at TGen symposium
Three undergraduate biochemistry students from Arizona State University's School of Molecular Sciences presented at the Helios Scholars TGen 2017 Intern Symposium on July 28, showcasing their work in biomedical research over the summer.
What if one day, we could teach our bodies to self-heal like a lizard’s tail, and make severe injury or disease no more threatening than a paper cut? Such is the vision, promise and excitement in the burgeoning field of regenerative medicine, now a major ASU initiative to boost 21st-century medical research discoveries.
Researchers lead by Raimund Fromme with Kevin Redding of the School of Molecular Sciences and the Biodesign Institute’s Center for Applied Structural Biology, in collaboration with scientists from Penn State University and the Center for Free-Electron Laser Science in Germany, have determined for the first time the structure of the photosynthetic reaction center in heliobacteria. This is significant since the heliobacteria reaction center preserves structural characteristics of the earliest reaction centers, and therefore provides important information on the evolution of photosynthesis.
In new research, Professor Alex Green uses computer software to design RNA sequences and demonstrates how living cells can be induced to carry out computations like tiny robots or computers. The results of his research have implications for drug design, green energy, diagnostic technologies, and even development of nanomachines.
As part of an international collaboration with researchers from the University of Illinois, Université Paris-Sud and the University of Virginia, Tom Moore, Ana Moore and Devens Gust of the School of Molecular Sciences recently shown how theory can be used to guide the design of a concerted electron–proton transfer process. In a recent paper in ACS Central Science, the group showed how a model system inspired by photosystem II exhibited one-electron oxidation that was coupled to two proton translocations, through a hydrogen-bonded network. The rational design of the coupled system has implications for managing proton activity at catalytic sites for redox-based energy conversion.
Arizona State University geoscientist Everett Shock has collaborated with a team of life scientists to study why a microorganism thriving in a hot spring in Yellowstone National Park draws its energy from low-quality geochemical energy supplies rather than rich ones. Professor Shock suggests that biological cost may be one of the reasons for this phenomenon.
In a new study, Wei Liu and his colleagues at Arizona State University’s School of Molecular Sciences and the Biodesign Institute join an international team with scientists from China, the United States, the Netherlands, and Denmark to explore a central component in glucose regulation. Their findings shed new light on a highly promising target for diabetes drug development.
May 16, 2017ASU molecular sciences graduate students excel
School of Molecular Sciences graduate students are being recognized by ASU’s College of Liberal Arts and the ASU Graduate and Professional Student Association for their achievements. These graduate students are being rewarded for their research in areas of energy storage and cancer biology, as well as for their mentorship, teaching excellence, and other efforts in the community.
May 2, 2017
Biochemistry senior shines with research
The accomplishments of School of Molecular Sciences bichemistry major Capria Rinaldi are highlighted in an article on graduating seniors for spring 2017 commencement. Capria excelled in both coursework and in the research lab. “In the lab, she is talented with her experimental skills, hardworking and always does more than she is asked to. My team and I are so proud of her and know that she will continue to do great things!” said Josh LaBaer, Virginia G. Piper Chair for Personalized Medicine in the School of Molecular Sciences and the executive director of ASU’s Biodesign Institute.
School of Molecular Sciences faculty members Steve Presse, Gary Moore and Ryan Trovitch are among the 14 National Science Foundation CAREER award recipients for 2017, a record number for ASU. CAREER awards are the NSF's most prestigious in support of junior faculty who most effectively integrate research and education.
April 21, 2017
Patrick Almhjell awarded Spring 2017 CLAS Dean's Medal
The College of Liberal Arts and Sciences has awarded the Dean's Medal for the School of Molecular Sciences to Patrick Almhjell. Patrick's major is Biochemistry and minor in Psychology and Biological Sciences. He has been conducting research in Professor Jeremy Mills’s biochemistry lab and Professor M. Foster Olive’s psychology lab since the fall of 2015, where he investigates amino acids and behavioral neuroscience, respectively.
April 21, 2017
Award ceremony recognizes outstanding students
The School of Molecular Sciences Annual Awards Ceremony recognized the School’s most talented and deserving undergraduate and graduate students with achievement awards and scholarships. The academic achievements of fourteen undergraduate and eight graduate students were celebrated, and eleven students and two faculty members were recognized for accomplishments in teaching.
April 18, 2017
Undergrad William Clark awarded APS Fellowship
Undergraduate biochemistry student William Clark is to be congratulated for just winning an American Physiological Society Undergraduate Summer Research Fellowship. The competition was worldwide and geared to providing research experiences to a wide range of students. Clark will be undertaking his research project in Karen Sweazea’s laboratory in ASU's School of Nutrition and Health Promotion in SOLS.
Gerhard Wagner, Elkan Rogers Blout Professor of Biological Chemistry and Molecular Pharmacology at the Harvard Medical School, is the Spring 2017 Eyring Lecturer at Arizona State University. The Eyring Lecture is a distinguished lecture series dedicated to stimulating discussion by renowned scientists who are at the cutting edge of their respective fields. Eyring lecturers give two presentations: The first is a more general lecture targeted towards a general audience interested in learning about contemporary scientific problems directly from the scientists contributing to the field, the second is a more technical presentation for practicing scientists and current students.
Josh LaBaer, Director of the Biodesign Virginia G. Piper Center for Personalized Diagnostics and professor in the School of Molecular Sciences, has been appointed as the new Executive Director of the Biodesign Institute at ASU. LaBaer is a leading researcher the discovery and validation of biomarkers for disease and is a pioneer in the rapidly emerging field of personalized medicine. LaBaer will lead the Biodesign Institute through a period of dramatic expansion in research capacity.
Four Junior faculty members from the School of Molecular Sciences have received national awards that highlight excellence in research and scholarship in the form of two NSF CAREER Awards, an Alfred P. Sloan Foundation Fellowship and a U.S. Air Forces Young Investigator Research Program award. Awards to junior faculty attract significant attention to the School as it builds a national reputation and recognition in the Molecular Sciences, that in turn enables the School to attract and hire talented young faculty members.
March 15, 2017
Ryan Trovitch receives NSF CAREER Award
Ryan Trovitch, assistant Professor in the School of Molecular Sciences, has received a competitive National Science Foundation CAREER award. CAREER awards identify exemplary teachers and scholars and are the most prestigious of those awarded by the National Science Foundation to junior faculty. Ryan's award is entitled "Development of Manganese Hydrosilylation Catalysts for Silicone Curing". The Trovich group is developing new low cost catalysts for silicone polymers, which represent a $15B/yr worldwide industry.
March 8, 2017
New Chemistry for Carbon Capture - Editor’s Choice
Controlled capture and release of carbon dioxide emitted from power plants represents a possible solution to the problem of accumulation of this greenhouse gas in the atmosphere. However, existing chemical methods for doing this consume large amounts of energy and are not technologically viable. In a recent perspective article in the journal American Chemical Society Energy Letters, Professor Dan Buttry and his group in the School of Molecular Sciences describe new electrochemical methods for controllable capture and release of carbon dioxide that have the potential to reduce these energy costs by a factor of two. This timely article was selected for highlighting as an American Chemical Society "Editors Choice" article.
Alex Green of the School of Molecular Sciences and the Biodesign Center for Molecular Design and Biomimetics has been awarded a prestigious 2017 Alfred P. Sloan Foundation Research Fellowship. The recipients of Sloan Research Fellowships are early-career scientists and scholars from a broad range of scientific disciplines who are on track to be the next-generation leaders in their fields. Alex has been recognized for his work on computationally designed functional RNAs.
February 14, 2017
Behind the Faucet: What impacts your drinking water quality?
Pierre Herckes recently gave a Dean of Science public lecture entitled "Behind the Faucet: What Impacts Your Drinking Water Quality". Pierre described contemporary issues related to water quality, using the recent problems in Flint, Michigan as an example. A panel of local experts on water from ASU, the Salt River Project and the City of Phoenix Water Services answered questions from the public.
Jeremy Babendure, adjunct professor in the School of Molecular Sciences, and also one of our many successful alumni, recently took a group of middle and high school students from Arizona to the west board room of the Eisenhower Executive Office Building, just steps from the White House.
December 18, 2016
Novel technique helps ID elusive molecules
Stuart Lindsey of the School of Molecular Sciences and Director of the Biodesign Center for Single Molecule Biophysics, has reported a method for identifying individual sugar and carbohydrate molecules using a nanopore sequencing method, which was originally developed in the Lindsay lab for sequencing amino and nucleic acids. This new technique could open the door to a new generation of analytic tools for carbohydrates that can be used in the diagnosis and treatment of disease.
December 19, 2016
Gary Moore Receives NSF CAREER Award
Gary Moore has received a prestigious National Science Foundation CAREER award to study the assembly of molecular redox catalysts on (semi)conducting substrates using polymeric interfaces, with the goal of improving fundamental understanding of photoactivated catalysis in complex environments, and developing methodologies to control nanoscale devices at the molecular level.
December 9, 2016
Havell Markus Awarded Fall 2016 CLAS Dean's Medal
The College of Liberal Arts and Sciences has awarded the Dean's Medal for the School of Molecular Sciences to Havell Markus. Havell has found success in all aspects of his academic career, being ranked at the top of all of his chemistry and biochemistry classes and in research performed as a Helios scholar on blood DNA extraction, bioinformatics and genomics at T-Gen.
December 8, 2016
Can nature regain control of the global carbon cycle?
Tom Moore was recently invited to contribute a Ted type talk at a symposium on "The environmental problem from pharmacy and chemistry : Ethics and aesthetics as fundamental tools", part of a series on "Dialogues on Human Ecology" at the The Pontifical Catholic University of Chile. Using evidence from current research and trends in policy, social, economic and science issues relevant to sustainability, Tom gives a highly personalized but fascinating account of how mankind can help nature regain control of the global carbon cycle.
Kate Spencer is graduating this month with a major in biochemistry from the School of Molecular Sciences. Through her senior honor’s thesis research in the Archaeological Chemistry Laboratory, she combined both archaeology and biogeochemistry to better understand how the environment, particularly altitude, affects different isotope systems.
December 1, 2016
Mayo Clinic-ASU seed grant program funds new research projects
Jia Guo has received a grant from the Mayo Clinic-ASU seed grant program, which is a part of the new Mayo Clinic/ASU Alliance for Health Care. The program funds promising new research collaborations between ASU faculty and Mayo Clinic researchers. Jia will collaborate with Nancy Lee of the Mayo Clinic to study “Imaging of functional distinct eosinophil subtypes within lung biopsies.” “This year’s Mayo-ASU Seed awardees represent some of the strongest collaborative work being done by the most promising teams across the two institutions,” said Cheryl Conrad, assistant vice president of research development at ASU Knowledge Enterprise Development.
November 11, 2016
ASU protein pioneer honored as innovator at governor’s celebration
School of Molecular Sciences researcher and Regents’ Professor Petra Fromme was recently honored as the Academic Innovator of the Year at the Governor’s Celebration of Innovation, the annual awards gala that honors technology leaders and innovators from across the state that is sponsored by the Arizona Technology Council and the Arizona Commerce Authority. Fromme, who is director of the Center for Applied Structural Discovery, leads a team of chemists, physicists and biologists who are studying membrane proteins, finding answers to disease and clean energy
November 4, 2016
Nobel Laureate Professor Tom Cech delivers 50th Eyring Lecture
The Eyring Lecture Series in the School of Molecular Sciences is an interdisciplinary distinguished lecture series dedicated to stimulating discussion by renowned scientists who are at the cutting edge of their respective fields. Each series consists of a lead-off presentation to help communicate the excitement and the challenge of this central science to the university and community. Past lecturers have included Nobel Laureates Ahmed Zewail, Jean-Marie Lehn, Harry Gray, Richard Smalley and Yuan T. Lee.
Professor Cech delivered the general lecture on November 3rd 2016 entitled "The Long Road to Precision Medicine: How Mutations Activate an "Immortality Gene" and Help Drive Cancer". He is Distinguished Professor at the University of Colorado Boulder, Director at University of Colorado BioFrontiers Institute, and Investigator at Howard Hughes Medical Institute. Cech's work has been recognized by many national and international awards and prizes, including the Heineken Prize of the Royal Netherlands Academy of Sciences (1988), the Albert Lasker Basic Medical Research Award (1988), the Nobel Prize in Chemistry (1989), and the National Medal of Science (1995). In 1987 Dr. Cech was elected to the U.S. National Academy of Sciences and also awarded a lifetime professorship by the American Cancer Society.
September 23, 2016
Grant to Explore an Efficient Way to Capture & Transfer Solar Energy
September 16, 2016
Cleanest Confirmation of Marcus Law
Spotlight on a Recent Journal of the American Chemical Society (JACS) Publication…
Dmitry Matyushov and co-workers from The School of Molecular Sciences and the Department of Physics at Arizona State University have recently reported a straightforward verification of Marcus (Nobel Laureate in Chemistry 1992) theory.
September 12, 2016
Protein complexes connected to Cystic Fibrosis characterized
In a recent paper in Science Advances, Wade Van Horn of the School of Molecular Sciences and the Biodesign Center for Personalized Diagnostics, together with colleagues from Vanderbilt and Northwestern Universities, have characterized the protein complex responsible for ion transport across membranes, and the mechanisms underlying its dysfunction in patients who suffer from cystic fibrosis.
June 14, 2016
A Linear Allotrope of Carbon?
Carbyne, an allotrope of carbon that has a linear chain of carbon atoms with alternating single and triple bonds, remains elusive. Theoretical work by Pilarisetty Tarakeshwar and Peter Busek together with the late Harold Kroto of Florida State University shows that a recent report claiming the production of carbyne missed the presence of gold atoms in the crystal structure. The metal stabilizes the carbon chains, and although not carbyne, metal stabilized carbynes could be an interesting class of materials says Busek.
In collaboration with researchers at MIT and the Baylor College of Medicine, Hao Yan and graduate student Fei Zhang have demonstrated an important new variant on the DNA origami method of forming complex DNA architectures that starts with the desired 3D shape and then generates the required DNA base sequence and folding pattern using a computer algorithm. This "top down" approach avoids the need to forward-design the complex Watson-Crick base-pairing manually and reduces human input into the details of DNA strand folding paths.
The College of Liberal Arts and Sciences has recognized Sahba Zaare as the highest achieving student in the School of Molecular Sciences at the spring convocation ceremony. Sabha who majored in biochemistry, was a previous recipient of the Merck Index Award and the Hypercube Award. Sabha performed research in the labs of both Chad Borges and also Kevin Redding.
Alexander Green and graduate student Duo Ma co-author a study describing a practical and low-cost diagnostic test for the Zika virus, based on toehold switch gene technology. The method uses toehold switch gene technology, also developed by Green and colleagues, where formation of a reporter protein via translation is blocked until exposed to RNA present in blood samples containing Zika.
February 16, 2016
Buseck and Anbar to study the origin of water on Earth
Arizona State University has received a $1.5 million award from the W.M. Keck Foundation’s Science and Engineering Research Grant Program to study the origin of Earth’s water and hydrogen. The project, entitled " Water from the Heavens: The Origins of Earth’s Hydrogen," will be headed by Principal Investigator and Regents’ Professor Peter Buseck, of the School of Earth and Space Exploration and the School of Molecular Sciences.
February 10, 2016
Chemical cages: New technique advances synthetic biology
In a recent publication in Nature Communications, Hao Yan and co-workers describe novel method for enhancing the reactivity of the critical biological catalysts enzymes. The technique involves the design of specialized, nanometer-scale cages, which self-assemble from lengths of DNA. The cages hold enzyme and substrate in close proximity, considerably accelerating the rate of reactions and shielding them from degradation.
February 1, 2016
A pioneer in exploring molecular structure
Paul V Galvin Professor Petra Fromme has joined the ranks of the highest faculty honor at the university, as Regents’ Professor. Fromme, a world expert on proteins, is a pioneer in using new technology to research their molecular structure and dynamics. As director of the new Center for Applied Structural Discovery at the Biodesign Institute, she leads 12 faculty and their students from different disciplines studying the structure and dynamics of proteins, potentially leading to improved manmade technologies.
Assistant Professor Nick Stephanopoulos is one of three ASU faculty, more than from any other university in the nation, to receive awards from the Air Forces Young Investigator Research Program. The award, “Peptide-DNA Tiles as Building Blocks for Complex Nanostructures” will support his work as part of the Biodesign Institute Center for Molecular Design and Biomimetics.
ASU scientists, in collaboration with Trinity College Dublin, have identified the mechanism of action of the important membrane-integral kinase enzyme diacylgylcerol. Diacylgylcerolis plays a role in bacterial wall synthesis by catalyzing conversion of diacylglycerol to phosphatidic acid. It's mechanism has been considered mysterious because its lipid substrates are hydrophobic and its co-substrate is the water soluble ATP. A detailed crystal structure analysis now supports a mechanism for direct transphosphorylation by this diminutive kinase.
November 20, 2015
Earth’s oxygen-rich atmosphere began in fits and starts
Earth's oxygen-rich atmosphere emerged as transient “whiffs” in shallow oceans around 2.5 billion years ago, according to new research involving ASU scientists. “One of the questions we ask is: ‘Did the evolution of photosynthesis lead directly to an oxygen-rich atmosphere? Or did the transition to today's world happen in fits and starts?" said Ariel Anbar, President’s Professor in the School of Earth and Space Exploration and the School of Molecular Sciences. “How and why Earth developed an oxygenated atmosphere is one of the most profound puzzles in understanding the history of our planet.”
October 20, 2015
ASU forms the new School of Molecular Sciences
In reponse to the evolution and maturation of the traditional disciplines of chemistry and biochemistry, the Department of Chemistry and Biochemistry at Arizona State University has reorganized into the new School of Molecular Sciences. The School aims to define a new approach to research and academics in the molecular sciences and to creat a use-inspired environment in which to train a new generation of undergraduate and graduate students.
Bacteria's ability to become resistant to antibiotics is a growing issue in health care. One way to combat this is to determine bacteria's antibiotic resistance in a given patient, but that often takes days. Professor Mark Hayes and his group scientists have developed a technique that can sort antibiotic-resistant from "susceptible" bacteria in a matter of minutes using novel microfluidic technology.
July 20 , 2015
Novel structures built from DNA emerge
DNA origami allows endlxessly varied molecular forms to be constructed in multiple dimensions. In a new study in Nature Nanotechnology from the Hao Yan and Yan Liu research groups, complex nano-forms displaying arbitrary wireframe architectures were created using new design rules. "Earlier design methods used strategies including parallel arrangement of DNA helices to approximate arbitrary shapes, but precise fine-tuning of DNA wireframe architectures that connect vertices in 3D space has required a new approach," Yan says.
ASU Engineering Professor Paul Westerhoff and School of Molecular Sciences Professor Pierre Herckes have identified the carcinogenic N-nitrosodimethylamine (NDMA), found in drinking water supplies, to be a degradation product of methadone. The work, featured in the PBS program Newshour, is significant not only because NDMA is a potent carcinogen, but because it uncovers a new ponential danger in the water supply. "If you live downstream from any population, then you're likely drinking someone's wastewater", says Westerhoff.
April 23, 2015
Key blood pressure drug seen in startling new detail
New work has revealed the fine details of how an experimental drug works to regulate blood pressure. The interdisciplinary team includes Paul V Galvin Professor Petra Fromme. “Uncovering the structure of the angiotensin receptor is a real breakthrough in the development of better drugs to regulate blood pressure,” Fromme says. It has been unraveled by a new technique called femtosecond crystallography, pioneered by researchers at ASU and their collaborators.
Lithium-ion batteries are one of the most popular types of rechargeable batteries for portable electronics, with a high energy density, no memory effect and only a slow loss of charge when not in use. Now, researchers at ASU are exploring new energy storage technology that could give the battery an even longer life cycle. Led by School of Molecular Sciences Professor Dan Buttry, he research also involves former undergraduate researcher Jarred Olsen and current graduate student Tylan Watkins.
February 16, 2015
ASU Secondary Ion Mass Spectrometry Facility
School of Molecular Sciences Professor Peter Williams together with colleagues from the School of Earth and Space Exploration have recieved a $1 million grant to operate their joint SIMS laboratories. SIMS is an analytical tool permitting measurements of elemental concentration and isotope ratios on extremely tiny areas, so that chemical and isotopic variability on scales from a few micrometers down to several nanometers can be determined.