Yuval Mazor

Biodesign A230B
1001 S. McAllister Ave.
Tempe
Assistant Professor
Faculty
TEMPE Campus
Mailcode
1604

Biography

Yuval Mazor received his Ph.D. and M.Sc. from the department of microbiology and biotechnology in Tel Aviv University doing research on the genetic basis of telomere maintenance and epigenetic gene silencing. He then joined the lab of Professor Nathan Nelson, also in Tel Aviv University, where he studied the structure of large photosynthetic complexes in cyanobacteria and plants. 

Mazor is currently assistant professor at Arizona State University's School of Molecular Sciences and The Biodesign Institute. He has previously taught BCH598/BCH494, Photosynthesis Past and Present, as well as BCH 561, A Lecture on the Structural Biology of Photosynthetic Systems.

Education

Ph.D., Tel Aviv University, 2009

Research Interests

Our primary focus is the structural biology of the membrane complexes involved in oxygenic photosynthesis. Photosynthetic organisms contain elaborate membrane systems called thylakoid membranes. In these membranes large reaction centers convert light into chemical energy. The photosynthetic reaction centers contain hundreds of light harvesting pigments, such as chlorophylls and carotenoids, oriented in a way which ensures efficient light harvesting. Around these reaction centers an elaborate system of antenna proteins and other enzymatic activities ensure a balance between beneficial chemical reactions, essential for the survival of the organism and unavoidable side reactions with toxic products. We want to develop a mechanistic understanding of these pathways based on structural, biochemical and genetic analysis. 

Publications

 

  1. Toporik H, Li J, Williams D, Chiu PLC, Mazor Y. “The structure of the stress-induced photosystem I-IsiA antenna supercomplex”, Nature Structural and Molecular biology, 2019, 26(6):443-449.
  2. Marco P, Kozuleva M, Eilenberg H, Mazor Y, Gimeson P, Kanygin A, Redding K, Weiner I, Yacoby I.” Binding of ferredoxin to algal photosystem I involves a single binding site and is composed of two thermodynamically distinct events.”, Biochim Biophys Acta, 2018, 1859(4), 234.
  3. Mazor Y, Borovikova A, Caspy I, Nelson N. (2017) “The structure of plant photosystem I supercomplex at 2.6 Å resolution.” Nature Plants 3, 17014.
  4. Mazor Y, Borovikova A, Nelson N. (2015) “The structure of plant photosystem I super-complex at 2.8 Å resolution.” eLife, e07433.
  5. Mazor Y, Nataf D, Toporik H, Nelson N. (2014) “Crystal structures of virus-like photosystem I complexes from the mesophilic cyanobacterium Synechocystis PCC 6803.” eLife, e01496.
  6. Mazor Y, Greenberg I, Toporik H, Beja O, Nelson N. (2012) “The evolution of photosystem I in light of phage-encoded reaction centres.". Phil. Trans. R. Soc. B, 367(1608)3400:5.
  7. Mazor Y, Toporik H, Nelson N. (2012) "Temperature-sensitive PSII and promiscuous PSI as a possible solution for sustainable photosynthetic hydrogen production". BBA, 1817(8):1122-6.
  8. Omer S, Kovacs A, Mazor Y, Gophna U. (2009) "Complex integration does not impair fitness in an experimental model of lateral gene transfer." Mol Biol Evol, 27(11):2441-5.
  9. Mazor Y, Kupiec M. (2009) "Developmentally regulated MAPK pathways modulate heterochromatin in Saccharomyces cerevisiae". NAR, Vol. 37(14):4839-49.
  10. Parnas O, Zipin-Roitman A, Mazor Y, Liefshitz B, Ben-Aroya S, Kupiec M. (2009) "The ELG1 clamp loader plays a role in sister chromatid cohesion." PLoS ONE 4(5): e5497.
  11. Smolikov S, Mazor Y, Krauskopf A.  (2004) "ELG1, a regulator of genome stability, has a role in telomere length regulation and in silencing." Proc Natl Acad Sci U S A. 101: 1656-1661.
  12. Marco P, Kozuleva M, Eilenberg H, Mazor Y, Gimeson P, Kanygin A, Redding K, Weiner I, Yacoby I.  (2018) "Binding of ferredoxin to algal photosystem I involves a single binding site and is composed of two thermodynamically distinct events."  BBA 1859:  234.

Courses

Fall 2019
Course NumberCourse Title
BCH 462General Biochemistry
BIO 495Undergraduate Research
Spring 2019
Course NumberCourse Title
BIO 494Special Topics
BCH 494Special Topics
BCH 501Current Topics in Biochemistry
PLB 558Molecular Mech Photosynthesis
BCH 568Molecular Mechanisms/Photosyn
Fall 2018
Course NumberCourse Title
BCH 367Elementary Biochemistry Lab
Spring 2018
Course NumberCourse Title
BCH 501Current Topics in Biochemistry
BCH 561Adv Topics in Biochemistry
Fall 2017
Course NumberCourse Title
BCH 367Elementary Biochemistry Lab
Spring 2017
Course NumberCourse Title
BCH 494Special Topics
BCH 598Special Topics